General information, not a diagnosis Method and limitations

Fact sheetVirus

Smallpox

Smallpox, due to smallpox virus, was declared eradicated by WHO in 1980. This sheet explains its historical context and its difference with the mpox.

Documentary Enrichment: · General information

Essentials

Human disease worldwide eradicated in 1980; no natural cases are currently circulating.

Agent
Variolic virus
Transmission or exposure
Respiratory tract · Close contact

Situation and vulnerability

There is no longer known natural circulation. Current activities concern health preparation and supervised research, rather than a common risk of daily life.

Signs and limits of their interpretation

Historically, high fever and fatigue preceded a rash that evolved to pustules and then crusts. Many current diseases also cause skin damage.

Diagnosis and monitoring

The history of eradication must guide interpretation: visual resemblance is not a diagnosis. The evaluation of an eruption first looks for the causes adapted to the context.

Official sources consulted on . Documentary summary, without medical rereading.

Check these benchmarks in the WHO reference →

Prevention and care

Do not deduct a smallpox from an eruption. A table of concern must be assessed medically; exceptional suspicion is the responsibility of the health authorities and specialized laboratories.

Practical issues

Does the mpox mean that the smallpox is back?

No. mpox and smallpox are due to distinct viruses, even if they belong to a related group. Cases of mpox do not affect the eradication of smallpox.

Preparing for an exchange with a professional

  • Date and evolution of a current eruption
  • Travel, contacts and associated symptoms
  • Historical issue or specific occupational exposure

Bring the full minutes and dates. This information facilitates evaluation; its collection must not delay an urgent appeal.

Individual decisionThe choice of a test, treatment or prevention depends on the local situation and recommendations. In case of distress, call 911.
A calm clinical consultation desk, blank folder, glass of water and an unmarked notebook. AI-generated illustration.
Prevention illustration — Variole — A calm clinical consultation desk, blank folder, glass of water and an unmarked notebook.
Image generated by artificial intelligence. AI illustration; it does not depict a disease, biological agent or diagnosis.

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Related fact sheets

These sheets share ways or contexts of exhibition in our catalogue. This reconciliation does not establish a differential diagnosis.

Compare Smallpox with associated pages →

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Further reading

These publications help you verify the concepts discussed. Disease records and directory entries each identify their sources.

The content modification date does not mean that every source has undergone a new medical review. Verification method and scope.