General information, not a diagnosis Method and limitations

Fact sheetParasite

Human African trypanosomiasis

Human African trypanosomiasis, or sleep disease, is mainly transmitted by tsetse flies. It can reach the nervous system.

Documentary Enrichment: · General information

Essentials

Sleep disease transmitted by infected tsetse flies in sub-Saharan Africa.

Agent
Trypanosoma brucei
Transmission or exposure
Vector

Situation and vulnerability

The gambiense form can evolve slowly in West and Central Africa; the rhodesi form evolves more rapidly in East and Southern Africa.

Signs and limits of their interpretation

Fever, headache, lymph nodes and pain may precede behavioural disorders, confusion, poor coordination and disruption of the sleep cycle.

Diagnosis and monitoring

The diagnosis combines suitable screening, confirmation of the parasite and stage evaluation. Analysis of cerebrospinal fluid may be required depending on the situation.

Official sources consulted on . Documentary summary, without medical rereading.

Check these benchmarks in the WHO reference →

Prevention and care

Early assessment prevents progression to neurological disease. Treatment depends on form and stage; prolonged follow-up may be necessary after treatment.

Practical issues

Is fatigue or bad sleep sufficient for diagnosis?

No: the name of the disease is not a test. Geographical exposure, examination and parasitic confirmation are necessary; other causes may produce these symptoms.

Preparing for an exchange with a professional

  • Specific regions and dates of stay
  • Fever onset and behavioural changes
  • Results of examinations and treatments

Bring the full minutes and dates. This information facilitates evaluation; its collection must not delay an urgent appeal.

Individual decisionThe choice of a test, treatment or prevention depends on the local situation and recommendations. In case of distress, call 911.
An empty specimen collection room, comfortable chair, unopened sterile supplies and soft light. AI-generated illustration.
Prevention illustration — Trypanosomiase humaine africaine — An empty specimen collection room, comfortable chair, unopened sterile supplies and soft light.
Image generated by artificial intelligence. AI illustration; it does not depict a disease, biological agent or diagnosis.

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Related fact sheets

These sheets share ways or contexts of exhibition in our catalogue. This reconciliation does not establish a differential diagnosis.

Compare African Human Trypanosomiasis with Associated Sheets →

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Further reading

These publications help you verify the concepts discussed. Disease records and directory entries each identify their sources.

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